85-6342-32　Filamin 1（Phospho Ser2152） Polyclonal Antibody 100ul　BT-AP06224

特徴

• 背景：The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins| transmembrane receptor complexes| and second messengers. Defects in this gene are a cause of several syndromes| including periventricular nodular heterotopias (PVNH1| PVNH4)| otopalatodigital syndromes (OPD1| OPD2)| frontometaphyseal dysplasia (FMD)| Melnick-Needles syndrome (MNS)| and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from human Filamin A around the phosphorylation site of Ser2152. AA range:2121-2170
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat, Monkey
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Filamin-A; FLNA; FLN; FLN1; Filamin-A; FLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin
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