85-6325-77 MUM1 Polyclonal Antibody 100ul BT-AP05664
特徴
- 背景：DNA double-strand breaks (DSBs) are potentially hazardous lesions that can be induced by ionizing radiation (IR), radiomimetic chemicals, or DNA replication inhibitors. Melanoma associated antigen (mutated) 1 (MUM1, EXPAND1) is a PWWP-domain containing chromatin binding protein involved in maintaining chromatin architecture of interphase chromosomes. In response to DNA damage, EXPAND1/MUM1 accumulates at sites of DNA double strand breaks through direct interaction with DNA repair factor 53BP1. Accumulation of EXPAND1/MUM1 at damaged DNA sites is thought to modify the structure of the chromatin and allow access to other DNA repair factors. 53BP1 activates the checkpoint kinase ATM and promotes DNA double strand break repair via nonhomologous end joining (NHEJ) repair pathway.
仕様
- サイズ：100ul
- 抗原：The antiserum was produced against synthesized peptide derived from the C-terminal region of human MUM1. AA range:661-710
- 免疫動物：Rabbit
- 交差性：Human;Mouse;Rat
- 適用：WB, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：melanoma associated antigen (mutated) 1
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6325-77
MUM1 Polyclonal Antibody 100ul
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85-6325-75
MUM1 Polyclonal Antibody 20ul
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85-6325-76
MUM1 Polyclonal Antibody 50ul
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