85-6322-42　MRGX1 Polyclonal Antibody 20ul　BT-AP05554

特徴

• 背景：MRGPRX1 (MAS Related GPR Family Member X1) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. rphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) (PubMed: 26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：MRGPRX1; MRGX1; SNSR3; SNSR4; Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 3/4
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