85-6319-91　MMP-1 Polyclonal Antibody 50ul　BT-AP05471

特徴

• 背景：MMP1 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Interstitial collagenase in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. MMP1 is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human MMP-1. AA range:411-460
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：MMP1; CLG; Interstitial collagenase; Fibroblast collagenase; Matrix metalloproteinase-1; MMP-1
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