85-6319-37　MLH3 Polyclonal Antibody 50ul　BT-AP05453

特徴

• 背景：MLH3 is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The mutL homolog 3 encoded by MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human MLH3. AA range:521-570
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：MLH3; DNA mismatch repair protein Mlh3; MutL protein homolog 3
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