85-6314-76　MDM2 Polyclonal Antibody 50ul　BT-AP05300

特徴

• 背景：MDM2 encodes a nuclear-localized E3 ubiquitin ligase. E3 ubiquitin-protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from the C-terminal region of human MDM2. AA range:381-430
• 免疫動物：Rabbit
• 交差性：Human
• 適用：IF, WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：MDM2; E3 ubiquitin-protein ligase Mdm2; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; p53-binding protein Mdm2
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