85-6307-18 LOST1 Polyclonal Antibody 20ul BT-AP05050
特徴
- 背景:TUSC5 (tumor suppressor candidate 5), also known as protein located at seventeen-p-thirteen point three 1, LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3), is a 177 amino acid multi-pass membrane protein that belongs to the CD225 family. Thought to play a role in fat metabolism, TUSC5 is highly expressed in mammary gland, heart, smooth muscle, skeletal muscle and stomach, with lower levels found in lung and brain. The gene encoding TUSC5 maps to human chromosome 17, which comprises over 2. % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, and is liked to predisposition of cancers of the ovary, colon, prostate gland and fallopian tubes.
仕様
- サイズ:20ul
- 抗原:The antiserum was produced against synthesized peptide derived from human TUSC5. AA range:1-50
- 免疫動物:Rabbit
- 交差性:Human
- 適用:WB, IF, ELISA
- クラス:IgG
- クロナリティ:Polyclonal
- 濃度:1 mg/ml
- 別名:TUSC5; IFITMD3; LOST1; Tumor suppressor candidate 5; Dispanin subfamily B member 1; DSPB1; Interferon-induced transmembrane domain-containing protein D3; Protein located at seventeen-p-thirteen point
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6307-20
LOST1 Polyclonal Antibody 100ul
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85-6307-18
LOST1 Polyclonal Antibody 20ul
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85-6307-19
LOST1 Polyclonal Antibody 50ul
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