85-6300-99　KLHL3 Polyclonal Antibody 20ul　BT-AP04845

特徴

• 背景：KLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human KLHL3. AA range:10-59
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：KLHL3; KIAA1129; Kelch-like protein 3
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