85-6299-76　SNTA1 Rabbit Polyclonal Antibody 50ul　BT-AP04804

特徴

• 背景：Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue.

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from human SNTA1
• 免疫動物：Rabbit
• 交差性：Human, Mouse
• 適用：WB
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：SNTA1
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