85-6288-10　Ikaros 3 Polyclonal Antibody 50ul　BT-AP04417

特徴

• 背景：IKZF3 encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. Zinc finger protein Aiolos is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human IKZF3. AA range:361-410
• 免疫動物：Rabbit
• 交差性：Human;Mouse
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：IKZF3; ZNFN1A3; Zinc finger protein Aiolos; Ikaros family zinc finger protein 3
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