85-6286-95　Rad50（Phospho-Ser635） Rabbit Polyclonal Antibody 100ul　BT-AP04379

特徴

• 背景：The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50| a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein| cooperating with its partners| is important for DNA double-strand break repair| cell cycle checkpoint activation| telomere maintenance| and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.

仕様

• サイズ：100ul
• 抗原：Synthesized phosho peptide around human Rad50 (Ser635)
• 免疫動物：Rabbit
• 交差性：Human, Rat, Mouse
• 適用：WB
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Rad50 ;Ser635; DNA repair protein RAD50; hRAD50; EC 3.6.-.-
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