85-6268-97　GPS2 Polyclonal Antibody 50ul　BT-AP03780

特徴

• 背景：GPS2 encodes G protein pathway suppressor 2 involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human GPS2. AA range:11-60
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：GPS2; G protein pathway suppressor 2; GPS-2
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