85-6256-45　Frizzled-6 Polyclonal Antibody 20ul　BT-AP03367

特徴

• 背景：FZD6 (frizzled class receptor 6) represents a member of the frizzled gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human FZD6. AA range:121-170
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：FZD6; Frizzled-6; Fz-6; hFz6
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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