85-6249-13　Factor VIII Polyclonal Antibody 50ul　BT-AP03124

特徴

• 背景：F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. F8 produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. DefectsF8 results in hemophilia A, a common recessive X-linked coagulation disorder.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human Factor VIII. AA range:2161-2210
• 免疫動物：Rabbit
• 交差性：Human;Mouse
• 適用：WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：F8; F8C; Coagulation factor VIII; Antihemophilic factor; AHF; Procoagulant component
• この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）

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