85-6247-01 ERI1 Polyclonal Antibody 50ul BT-AP03054
特徴
- 背景：ERI1, also named as HEXO, 3'HEXO and THEX1, contains one exonuclease domain and one SAP domain. The SAP domain is necessary for binding to the stem-loop structure of histone mRNAs and to form the ternary complex with SLBP, but not for 3'-end histone mRNA exonuclease activity. It is a RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is able to bind other mRNAs. ERI1 is required for 5. S rRNA 3'-end processing. It also binds to 5. s ribosomal RNA. ERI1 binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
仕様
- サイズ：50ul
- 抗原：The antiserum was produced against synthesized peptide derived from human ERI1. AA range:261-310
- 免疫動物：Rabbit
- 交差性：Human;Mouse;Rat
- 適用：WB, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：ERI1; 3'EXO; THEX1; 3'-5' exoribonuclease 1; 3'-5' exonuclease ERI1; Eri-1 homolog; Histone mRNA 3'-end-specific exoribonuclease; Histone mRNA 3'-exonuclease 1; Protein 3'hExo; HEXO
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6247-01
ERI1 Polyclonal Antibody 50ul
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85-6246-99
ERI1 Polyclonal Antibody 20ul
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85-6247-02
ERI1 Polyclonal Antibody 100ul
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