85-6231-13 DCC Polyclonal Antibody 50ul BT-AP02517
特徴
- 背景:DCC encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein DCC netrin 1 receptor localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.
仕様
- サイズ:50ul
- 抗原:The antiserum was produced against synthesized peptide derived from human DCC. AA range:441-490
- 免疫動物:Rabbit
- 交差性:Human;Mouse;Rat
- 適用:WB, IF, ELISA
- クラス:IgG
- クロナリティ:Polyclonal
- 濃度:1 mg/ml
- 別名:DCC; IGDCC1; Netrin receptor DCC; Colorectal cancer suppressor; Immunoglobulin superfamily DCC subclass member 1; Tumor suppressor protein DCC
- この商品は法規制を確認しておりません。(法規制によって販売できない場合もございます)
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- TEL:06-6447-8641
- FAX:06-6447-8642
- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6231-13
DCC Polyclonal Antibody 50ul
|
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85-6231-12
DCC Polyclonal Antibody 20ul
|
|
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85-6231-14
DCC Polyclonal Antibody 100ul
|
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