85-6225-60　DUX4 Rabbit Polyclonal Antibody 20ul　BT-AP02335

特徴

• 背景：This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants.

仕様

• サイズ：20ul
• 抗原：Synthesized peptide derived from human DUX4
• 免疫動物：Rabbit
• 交差性：Human, Rat, Mouse
• 適用：WB
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：DUX4
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