85-6223-42　CSB Polyclonal Antibody 20ul　BT-AP02263

特徴

• 背景：ERCC6 encodes a DNA-binding protein that is important in transcription-coupled excision repair. The ERCC excision repair 6, chromatin remodeling factor has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID: 267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human ERCC6. AA range:141-190
• 免疫動物：Rabbit
• 交差性：Human
• 適用：IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：ERCC6; CSB; DNA excision repair protein ERCC-6; ATP-dependent helicase ERCC6; Cockayne syndrome protein CSB
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