85-6219-79 COT Polyclonal Antibody 50ul BT-AP02142
特徴
- 背景：MAP3K8 is an oncogene that encodes a member of the serine/threonine protein kinase family. Mitogen-activated protein kinase 8 localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.
仕様
- サイズ：50ul
- 抗原：The antiserum was produced against synthesized peptide derived from human COT. AA range:256-305
- 免疫動物：Rabbit
- 交差性：Human;Mouse;Rat
- 適用：WB, IHC-p, IF, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：MAP3K8; COT; ESTF; Mitogen-activated protein kinase kinase kinase 8; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot; Tumor progression locus 2; TPL-2
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6219-80
COT Polyclonal Antibody 100ul
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85-6219-78
COT Polyclonal Antibody 20ul
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85-6219-79
COT Polyclonal Antibody 50ul
|
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