85-6217-85　COL25A1 Polyclonal Antibody 50ul　BT-AP02078

特徴

• 背景：COL25A1 (collagen type XXV alpha 1 chain) encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for COL25A1.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from human Collagen XXV alpha1. AA range:101-150
• 免疫動物：Rabbit
• 交差性：Human;Mouse
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：COL25A1; Collagen alpha-1(XXV) chain; Alzheimer disease amyloid-associated protein; AMY; CLAC-P
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