85-6217-49　Cortactin（Phospho Tyr466） Polyclonal Antibody 50ul　BT-AP02066

特徴

• 背景：This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis| the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from mouse Cortactin around the phosphorylation site of Tyr466. AA range:441-490
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat, Monkey
• 適用：WB, IHC-p, IF, ICC, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Src substrate cortactin; CTTN; EMS1; Src substrate cortactin; Amplaxin; Oncogene EMS1
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