85-6215-21 Clock Polyclonal Antibody 20ul BT-AP01990
特徴
- 背景：Clock circadian regulator encoded by CLOCK plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in CLOCK may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.
仕様
- サイズ：20ul
- 抗原：The antiserum was produced against synthesized peptide derived from human Clock. AA range:241-290
- 免疫動物：Rabbit
- 交差性：Human;Mouse;Rat
- 適用：WB, IHC-p, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：CLOCK; BHLHE8; KIAA0334; Circadian locomoter output cycles protein kaput; hCLOCK; Class E basic helix-loop-helix protein 8; bHLHe8
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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85-6215-21
Clock Polyclonal Antibody 20ul
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85-6215-22
Clock Polyclonal Antibody 50ul
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85-6215-23
Clock Polyclonal Antibody 100ul
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