85-6204-45　Cdk4 Polyclonal Antibody 50ul　BT-AP01631

特徴

• 背景：Cyclin-dependent kinase 4 encoded by CDK4 is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16 (INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16 (INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

仕様

• サイズ：50ul
• 抗原：The antiserum was produced against synthesized peptide derived from the N-terminal region of human CDK4. AA range:1-50
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat
• 適用：IF, WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：CDK4; Cyclin-dependent kinase 4; Cell division protein kinase 4; PSK-J3
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