85-6192-49　Cathepsin B Polyclonal Antibody 100ul　BT-AP01235

特徴

• 背景：CTSB encodes a member of the C1 family of peptidases. Alternative splicing of CTSB results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein (cathepsin B) has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of CTSB have been identified.

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from the Internal region of human CTSB. AA range:200-250
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：CTSB; CPSB; Cathepsin B; APP secretase; APPS; Cathepsin B1
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