85-6190-76　CAS Polyclonal Antibody 100ul　BT-AP01176

特徴

• 背景：Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein (chromosome segregation 1 like) may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for CSE1L.

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from human CSE1L. AA range:1-50
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, IHC-p, IP, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：CSE1L; CAS; XPO2; Exportin-2; Exp2; Cellular apoptosis susceptibility protein; Chromosome segregation 1-like protein; Importin-alpha re-exporter
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