85-6180-35 Bag-3 Polyclonal Antibody 20ul BT-AP00819
特徴
- 背景：BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
仕様
- サイズ：20ul
- 抗原：The antiserum was produced against synthesized peptide derived from the Internal region of human BAG3. AA range:311-360
- 免疫動物：Rabbit
- 交差性：Human
- 適用：WB, IHC-p, ELISA
- クラス：IgG
- クロナリティ：Polyclonal
- 濃度：1 mg/ml
- 別名：BAG3; BIS; BAG family molecular chaperone regulator 3; BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; Docking protein CAIR-1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
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