85-6179-79　Bim（Phospho-Ser69） Rabbit Polyclonal Antibody 100ul　BT-AP00800

特徴

• 背景：The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF)| as well as by the forkhead transcription factor FKHR-L1| which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.

仕様

• サイズ：100ul
• 抗原：Synthesized phosho peptide around human Bim (Ser69)
• 免疫動物：Rabbit
• 交差性：Human, Mouse
• 適用：WB
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Bim ;Ser69 ; Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacting mediator of cell death
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