85-6176-29　FANCD2（Phospho Ser222） Polyclonal Antibody 20ul　BT-AP00681

特徴

• 背景：The Fanconi anemia complementation group (FANC) currently includes FANCA| FANCB| FANCC| FANCD1 (also called BRCA2)| FANCD2| FANCE| FANCF| FANCG| FANCI| FANCJ (also called BRIP1)| FANCL| FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability| hypersensitivity to DNA crosslinking agents| increased chromosomal breakage| and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage| resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repai

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human FANCD2 around the phosphorylation site of Ser222. AA range:188-237
• 免疫動物：Rabbit
• 交差性：Human, Mouse, Rat
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：Fanconi anemia group D2 protein; FANCD2; FACD; Fanconi anemia group D2 protein; Protein FACD2
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