85-6171-76　APOBEC3A Polyclonal Antibody 100ul　BT-AP00525

特徴

• 背景：APOBEC3A is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.

仕様

• サイズ：100ul
• 抗原：The antiserum was produced against synthesized peptide derived from human APOBEC3A. AA range:27-76
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1
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