85-6171-35　APC5 Polyclonal Antibody 20ul　BT-AP00512

特徴

• 背景：ANAPC5 encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200
• 免疫動物：Rabbit
• 交差性：Human
• 適用：WB, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
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