85-6169-21　Amyloid-Beta Polyclonal Antibody 50ul　BT-AP00431

特徴

• 背景：APP (amyloid beta precursor protein) encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in APP have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for APP.

仕様

• サイズ：50ul
• 抗原：Synthesized peptide derived from Amyloid-β at AA range: 221-270
• 免疫動物：Rabbit
• 交差性：Human;Mouse;Rat
• 適用：IF, WB, IHC-p, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：amyloid beta (A4) precursor protein
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