85-6159-95　ABCG2 Polyclonal Antibody 20ul　BT-AP00110

特徴

• 背景：The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1| MDR/TAP| MRP| ALD| OABP| GCN20| White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein| this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta| which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

仕様

• サイズ：20ul
• 抗原：The antiserum was produced against synthesized peptide derived from human ABCG2. AA range:289-338
• 免疫動物：Rabbit
• 交差性：Human, Rat, Mouse
• 適用：WB, IHC-p, IF, ELISA
• クラス：IgG
• クロナリティ：Polyclonal
• 濃度：1 mg/ml
• 別名：ABCG2; ABCG2; ABCP; BCRP; BCRP1; MXR; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; CD antigen CD338
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