85-6156-08 ［取扱停止］Skeletal Receptor Tyrosine-protein Kinase, Active, Recombinant, Human Muscle, His-Tag, aa24-495 (MUSK) 20ug 587037
特徴
- Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle.
- Partial recombinant protein corresponding to aa24-495 from human Skeletal receptor tyrosine-protein kinase, fused to 6xHis-Tag at N-terminal, expressed in E. coli.
- Molecular Weight:~56.5kD
- Biological Activity:Measured by ADP-Glo Kinase detection kit. The EC50 of MUSK is 2.65-3.58ug/ml.
- Amino Acid Sequence:LPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDI
- Storage and Stability:Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：20ug
- Source Antigen：Recombinant, E.coli
- Grade：Highly Purified
- Purity：≥95% (SDS-PAGE)
- Form：Supplied as a lyophilized powder from Tris-HCl, pH 8.0, 6% trehalose. Reconstitute with sterile ddH2O, 0.1% BSA to a concentration of 0.1-1mg/ml.
- Molecular Weight Non Ab：56.5
- Swiss Prot Number：O15146
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