85-6156-05 Regulator of G-protein Signaling 17, Active, Recombinant, Human, GST-Tag, aa1-210 (RGS17) 100ug 587035
特徴
- Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.
- Recombinant protein corresponding to aa1-210 from Regulator of G-protein signaling 17, fused to GST-Tag at N-terminal, expressed in E.coli.
- Molecular Weight:~51.4kD
- Biological Activity:Measured by its binding ability in a functional ELISA. Immobilized AQP1 at 2ug/ml can bind human RGS17, the EC50 of human RGS17 protein is 31.63-34.44ug/ml.
- Amino Acid Sequence:MRKRQQSQNEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKSFVESTAGSSSES
- Storage and Stability:Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Source Antigen:Recombinant, E.coli
- Grade:Highly Purified
- Purity:≥85% (SDS-PAGE)
- Form:Supplied as a lyophilized powder from human Tris-HCl, 50% glycerol. Reconstitute with sterile ddH2O, 0.1% BSA to a concentration of 0.1-1mg/ml.
- Molecular Weight Non Ab:51.4
- Swiss Prot Number:Q9UGC6
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