85-6155-65 MHC Class I Polypeptide-related Sequence A, Active, Recombinant, Human, hFc-Tag, aa23-308 (MICA) 10ug 587014
特徴
- Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
- Partial recombinant protein corresponding to aa23-308 from human MHC class I polypeptide-related sequence A, fused to hFc-Tag at C-terminal, expressed in Mammalian cells.
- Molecular Weight:~59.9kD
- Biological Activity:The ED50 as determined by its ability to bind Human N2DL2 in functional ELISA is less than 5ug/ml.
- Amino Acid Sequence:AEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKVLVLQSHWQ
- Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
- Size:10ug
- Source Antigen:Recombinant, Mammalian cell
- Grade:Highly Purified
- Purity:≥95% (SDS-PAGE) Endotoxin: ≤1EU/ug (LAL)
- Form:Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with sterile ddH2O, 0.1% BSA to a concentration of 0.1-1.0mg/ml.
- Molecular Weight Non Ab:59.9
- Swiss Prot Number:Q29983
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