85-6153-71　［受注停止］Growth/differentiation Factor 6, Recombinant, Human, aa336-455 (GDF6) 10ug　586915

特徴

• Growth factor that controls proliferation and cellular differentiation in the retina and bone formation. Plays a key role in regulating apoptosis during retinal development. Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map.
• Recombinant protein corresponding to aa336-455 from human Growth/differentiation factor 6, expressed in E. coli.
• Molecular Weight:~13.6kD
• Biological Activity:Fully biologically active when compared to standard. The ED50 as determined by inducing alkaline phosphatase production of murine ATDC5 cells is less than 2.0μg/ml, corresponding to a specific activity of >500IU/mg.
• Amino Acid Sequence:TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.