85-6153-13 [取扱停止]Fibroblast Growth Factor 19, Active, Recombinant, Human, His-Tag, aa27-216 (FGF19) 10ug 586886
特徴
- Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
- Partial Recombinant protein corresponding to aa27-216 from human Fibroblast growth factor 19, fused to 6X His-Tag at N-terminal, expressed in E.coli.
- Molecular Weight:~23.5kD
- Biological Activity:The ED50 as determined by its ability to bind Human FGF R3 in functional ELISA is less than 15ug/ml.
- Amino Acid Sequence:FSDAGPHVHYGWGDPIRLRHLYTSGPHGLSSCFLRIRADGVVDCARGQSAHSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHRLPVSLSSAKQRQLYKNRGFLPLSHFLPMLPMVPEEPEDLRGHLESDMFSSPLETDSMDPFGLVTGLEAVRSPSFEK
- Storage and Stability:Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:10ug
- Source Antigen:Recombinant, E.coli
- Grade:Highly Purified
- Purity:≥95% (SDS-PAGE) Endotoxin: ≤1EU/ug (LAL)
- Form:Supplied as a lyophilized powder from 20mM PBS, pH 7.4. Reconstitute with sterile ddH2O, to a concentration of 0.1-1mg/ml.
- Molecular Weight Non Ab:23.5
- Swiss Prot Number:O95750
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