85-6143-76　Spike Glycoprotein, Recombinant, Avian Infectious Bronchitis Virus, aa300-520, His-Tag 100ug　586389

特徴

• S1 attaches the virion to the cell membrane by interacting with cell receptors, initiating the infection.; S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
• Source:Recombinant protein corresponding to aa300-520 from Avian infectious bronchitis virus Spike glycoprotein, fused to 6X His-Tag at C-terminal, expressed in Mammalian cell.
• Molecular Weight:~27kD
• Amino Acid Sequence:ESDYMYGSYHPSCKFRLETINNGLSFNPLSVSLGYGPIQGGCKQSVFENRATCCYAYSYNGPPLCKGVYRGELTKSFECGLLVFVTKTDGSRIQTRNEPFTLTQHNYNNITLDRCVEYNIYGRVGQGFITNVTNYAINYNYLADGGMAILDTSGAIDIFVVQGEYGLNYYKVNPCEDVNQQFVVSGGKLVGILTSRNETGSQPLENQFYIKIINGTRRSRR
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.