In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.; (Microbial infection) Recognition of M.tuberculosis by dendritic cells may occur partially via this molecule. Can recognize, bind, and opsonize pathogens to enhance their elimination by alveolar macrophages.
Source:Recombinant protein corresponding to aa21-248 from human Pulmonary surfactant-associated protein A1, fused to 6X His-Tag at N-terminal, expressed in Yeast.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:20ug
Source Antigen:Recombinant, Yeast
Grade:Purified
Purity:≥85% (SDS-PAGE)
Form:Supplied as a liquid in Tris, pH 8.0, 6% trehalose, 50% glycerol