85-6129-67 Omega-hexatoxin-Hv1a, Recombinant, Hadronyche versuta, aa1-37, His-SUMO-Tag 100ug 585634
特徴
- Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons. Lethal to many insect species but not toxic to mammals. May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels. An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A and Cav2.2/CACNA1B calcium channel of rats. As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.
- Source:Recombinant protein corresponding to aa1-37 from Hadronyche versuta Omega-hexatoxin-Hv1a, fused to 6X His-SUMO-Tag at N-terminal, expressed in E.coli.
- Molecular Weight:~20.1kD
- Amino Acid Sequence:SPTCIPSGQPCPYNENCCSQSCTFKENENGNTVKRCD
- Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
- Size：100ug
- Source Antigen：Recombinant, E. coli
- Grade：Purified
- Purity：≥90% (SDS-PAGE)
- Form：Supplied as a liquid in Tris, pH 8.0, 6% trehalose, 50% glycerol
- Molecular Weight Non Ab：20.1
- Swiss Prot Number：P56207
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
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85-6129-66
Omega-hexatoxin-Hv1a, Recombinant, Hadronyche versuta, aa1-37, His-SUMO-Tag 20ug
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85-6129-67
Omega-hexatoxin-Hv1a, Recombinant, Hadronyche versuta, aa1-37, His-SUMO-Tag 100ug
|
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