85-6115-77　HTH-type Quorum Sensing-dependent Transcriptional Regulator VjbR, Recombinant, Brucella abortus, aa1-259, His-Tag 20ug　584890

特徴

• Transcriptional regulator involved in the global control of Brucella gene expression. Mediates the effects of the quorum sensing autoinducer C12-HSL (N-dodecanoyl-homoserine lactone) on a large and diverse number of genes. Binds with high specificity to a large number of sites distributed across the genome. The VjbR-binding motif contains an asymmetric 16-bp consensus sequence, an unusual feature among LuxR-type regulators. May directly modulate expression of many genes, including virulence determinants, components of the respiratory chain, efflux systems, elements predicted to participate in ion transport and adaptation to stress, uncharacterized proteins, as well as transcriptional regulators probably responsible for the observed indirect VjbR-mediated effects.
• Source:Recombinant protein corresponding to aa1-259 from Brucella abortus HTH-type quorum sensing-dependent transcriptional regulator VjbR, fused to 6X His-Tag at N-terminal, expressed in Yeast.
• Molecular Weight:~30.6kD
• Amino Acid Sequence:MSLDLVHFPNYKKTFFGSSFQSDTLALLTRIRDEIGCRYVTHTYRGRVGDCTKVNSADLTVLMTLPATWVARYSSKNYFAIDPVFQEDAPYYRNDTSAIARDLKEDADICPAVAELLHDAEKHGLGNLFIAVSARNPKGVAGCTVFTFEVEDEDRTQFLARMRPRLLSLAGIIHGTVCGCKDANSVASLLTPREVDCLRWAANGKTDGEIAEILSIARWTVVTYLQNAKIKLNCSNRTSAVATALSLGIIDMPEVQHLV
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.