85-6093-85　ATP-dependent Translocase ABCB1, Recombinant, Human, aa236-297, His-Tag 100ug　583721

特徴

• Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
• Source:Recombinant protein corresponding to aa236-297 from human ATP-dependent translocase ABCB1, fused to 6X His-Tag at N-terminal, expressed in E.coli.
• Molecular Weight:~10.8kD
• Amino Acid Sequence:LSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANI
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：100ug
• Source Antigen：Recombinant, E. coli
• Grade：Purified
• Purity：≥90% (SDS-PAGE)
• Form：Supplied as a liquid in Tris, pH 8.0, 6% trehalose, 50% glycerol
• Molecular Weight Non Ab：10.8
• Swiss Prot Number：P08183
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