85-6089-05 A Disintegrin and Metalloproteinase with Thrombospondin Motifs 4, Recombinant, Human, aa213-319, GST-Tag 20ug 583461
特徴
- Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
- Source:Recombinant protein corresponding to aa213-319 from human A disintegrin and metalloproteinase with thrombospondin motifs 4, fused to GST-Tag at N-terminal, expressed in E.coli.
- Molecular Weight:~39.0kD
- Amino Acid Sequence:FASLSRFVETLVVADDKMAAFHGAGLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVILGSGEEGPQVGPSAAQTLRSFCAWQRGLNTPEDSDPDHFDTAILFTRQ
- Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
- Size:20ug
- Source Antigen:Recombinant, E. coli
- Grade:Purified
- Purity:≥85% (SDS-PAGE)
- Form:Supplied as a liquid in Tris, pH 8.0, 6% trehalose, 50% glycerol
- Molecular Weight Non Ab:39
- Swiss Prot Number:O75173
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