85-6086-19　［取扱停止］Measles Virus Lysate 100ug　497182

特徴

• Measles virus (MeV) is a single stranded negative-sense RNA virus, which belongs to the Morbillivirus genus of the family Paramyxoviridae.
• Measles is a highly contagious disease caused by the measles virus. It is a globally widespread disease that affects children but can also cause disease in unvaccinated adults. Humans are the only known host of measles virus and infection is spread from person-to-person via respiratory aerosol droplets, nasal secretions or through direct contact with infected individuals.
• Measles virus infection causes a febrile disease with a characteristic maculopapular rash that occurs 3-5 days after the onset of fever. Other non-specific symptoms include a cough, runny nose and conjunctivitis. In addition, MeV targets cells of the immune system and lymphoid tissues causing transient immunosuppression that can last several months or years.
• The disease is typically self-limiting but can cause complications in pregnant women, young infants, immunocompromised individuals, and in cases where severe malnutrition is a factor. Clinical complications include encephalitis, blindness, diarrhea, dehydration and pneumonia.
• Since the introduction of a safe and effective vaccine in the 1960’s, global cases of Measles have been in decline. However, measles is still endemic in countries where vaccination coverage is inconsistent and is still a major cause of morbidity and mortality in these countries (WHO).
• Source: Measles Virus Lysate, strain Measles virus, expressed in Vero cell line. 
• Applications: Suitable for use in Western Blot and Dot Blot. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Inactivation:Purified virions were lysed in 0.6M KCl containing 0.5% Triton X-100, and then subjected to heat inactivation.
• Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.