Feline respiratory disease complex is a group of respiratory illnesses caused by a number of organisms that can cause infection alone or together. It includes those illnesses with signs including inflammation of the nasal and sinus linings, inflammation of the eye lining (conjunctivitis), excessive tear production, salivation, and mouth sores. The principal diseases are feline viral rhinotracheitis (also called feline herpesvirus type 1; FHV-1) and feline calicivirus, although other diseases may also be involved, including feline infectious peritonitis virus (Kuehn, 2020).
The majority of feline upper respiratory infections are caused by feline viral rhinotracheitis (FVR), although the incidence of feline calicivirus may be higher in some populations of felines. Natural transmission of these agents occurs via aerosol droplets and fomites. The onset of FVR is characterised by fever, frequent sneezing, inflamed eyes (conjunctivitis), inflammation of the lining of the nose (rhinitis), and often salivation. Severely affected felines may develop mouth inflammation with sores, and inflammation of the cornea. Symptoms may last for 5-10 days in milder cases and up to 6 weeks in severe cases. The occurrence of severe viral upper respiratory disease is rare in adult, properly vaccinated felines. The outlook is generally good except for young kittens and older felines (Povey, 1979; Maes et al., 1984; Kuehn, 2020). Antiviral drugs developed for the treatment of humans infected with herpesviruses have been used to treat cats infected with FVR, with varying degrees of success (Thomasy & Maggs, 2016). Several intranasal modified-live virus FVR-FCV vaccines are available.
Source:Feline Panleukopenia Virus, strain C-27, from CRFK cells.
Applications:Suitable for use in ELISA. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
