Chikungunya virus (CHIKV) belongs to the genus Alphavirus, a member of the Togaviridae family of viruses. Chikungunya fever is a mosquito-borne disease that was first identified in Tanzania in 1953. Since 2004 there have been extensive outbreaks in Africa and Asia. In 2013 the first cases were identified in the Caribbean, and by September 2014 more than 650,000 cases had been reported in the Americas. Chikungunya fever is a febrile illness that usually starts 2–4 days after chikungunya virus infection. Patients present with clinical symptoms that include high fever, rash, headache, vomiting, myalgia, and severe joint pain. Most cases resolve after a few days but joint pain may persist for several months in some patients (CDC).
CHIKV is transmitted through the bite of infected Aedes aegypti and Aedes albopictus. These mosquitos also transmit Dengue Virus, and the clinical symptoms of infection are also similar. Differential diagnosis is therefore an important consideration in areas where other flaviviruses such as Dengue co-circulate.
Currently, there are no effective licensed vaccines for the prevention of Chikungunya fever or antiviral drugs available for the treatment of the disease.
Source: Chikungunya Virus Lysate, expressed in Vero cell line.
Applications:Suitable for use in ELISA. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Inactivation:Purified virions were lysed in 0.6M KCl containing 0.5% Triton X-100, and then subjected to heat inactivation.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Source Antigen：Recombinant, Vero Cells
Grade：Purified
Purity：Purified by sucrose density gradient ultracentrifugation.
