85-6085-45　［取扱停止］Canine Adenovirus 2, Serotype 2 100ug　497101

特徴

• Several strains of adenovirus exist, but two clinically significant adenovirus types have been identified in canines: adenovirus type 1 (CAdV-1) and adenovirus type 2 (CAdV-2). They are sometimes mistaken for canine herpesvirus. Both adenoviruses are spread similarly, but the resulting diseases are very different. Canine adenovirus 1 (Canine mastadenovirus A) is a nonenveloped DNA virus, which is antigenically related to CAdV-2. CAdV-1 infection is the cause of infectious canine hepatitis, a severe liver disease in canines and other canids, including coyotes, foxes, wolves; and in bears. Vaccination has made the disease rare in many countries in which it was endemic. Deaths from infectious canine hepatitis are usually sporadic, although small outbreaks can occur among young canines in kennels. The mortality rate for clinically expressed ICH is 10-30%. CAdV-2 is a member of the kennel cough complex e.g. a canine-type cold. Kennel cough is produced when more than one virus, bacteria and other multiple pathogens are combined and usually resolves on its own. Death from kennel cough is extremely rare, unless the animal has other serious concurrent conditions that are immune suppressant (terminal cancer, systemic immune deficiency). Viruses are spread from canine-to-canine by interactions through infected respiratory secretions or contact with contaminated feces or urine with higher risk of exposure in shelters, rescue centers, and breeding kennels. Vaccines are available and vaccination against CAdV-2 provides cross-protection for CAdV-1 (Decaro et al., 2008).
• Source: Canine Adenovirus 2, strain Serotype 2, expressed in A-72 cells.
• Applications: Suitable for use in ELISA. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Inactivation:UV and detergent inactivated.
• Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.