85-6085-06　TNFRSF4, Recombinant, Mouse, aa20-211, hIgG-His-Tag 20ug　497087

特徴

• TNFRSF4, also known as CD134, is a member of the TNFR-superfamily of receptors. This protein is a receptor for TNFSF4/OX40L/GP34 and a costimulatory molecule implicated in long-term T-cell immunity. OX40-OX40L interactions regulate antigen-specific T-cell expansion and survival, cytokine production. It also modulates cytokine receptor signalling. Therefore the interaction between TNFRSF4 and CD40L plays a key role in the development of multiple imflammatry and autoimmune disease. It has been implicated in the pathologic cytokine storm associated with certain viral infections, including the H5N1 bird flu.
• Recombinant protein corresponding to aa20-211 from mouse TNFRSF4, fused to hIgG-His-tag at C-terminal, expressed in HEK293 cells.
• Molecular Weight:~48.6kD
• Amino Acid Sequence:＜DGSM＞VTARRL NCVKHTYPSG HKCCRECQPG HGMVSRCDHT RDTLCHPCET GFYNEAVNYD TCKQCTQCNH RSGSELKQNC TPTQDTVCRC RPGTQPRQDS GYKLGVDCVP CPPGHFSPGN NQACKPWTNC TLSGKQTRHPASDSLDAVCE DRSLLATLLW ETQRPTFRPT TVQSTTVWPR TSELPSPPTL VTPEGP＜LEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.