85-6084-39　［受注停止］IL-5, Recombinant, Canine, aa22-134, His-Tag 20ug　497046

特徴

• IL-5, also known as interleukin-5, is a member of the hematopoietin receptor superfamily and is comprised of a cytokine-specific alpha chain and the common beta chain that is shared among these cytokines for signaling. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunoglobulin secretion. It related hematopoietic cytokines that are important for allergic inflammation. It is a lineage-specific cytokine for eosinophilpoiesis and plays an important part in diseases associated with increased eosinophils, such as asthma.
• Recombinant protein corresponding to aa22-134 from canine IL-5, fused to His-Tag at C-terminal, expressed in Baculovirus.
• Molecular Weight:~13.9kD
• Biological Activity:Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤15ng/ml.
• Amino Acid Sequence:VENPMNRLVA ETLTLLSTHR TWLIGDGNLM IPTPENKNHQ LCIKEVFQGI DTLKNQTAHG EAVDKLFQNL SLIKEHIERQ KKRCAGERWR VTKFLDYLQV FLGVINTEWT PES＜HHHHHH＞
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.