85-6084-25　FOLR2, Recombinant, Human, aa22-230, His-Tag 20ug　497039

特徴

• FOLR2, also known as Folate receptor beta, is a member of the folate receptor (FLOR) family. Members of this gene family have a high affinity for folate and folic acid analogs at neutral pH. And they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. It was originally thought to exist only in placenta, but is also expressed in placenta, cells of the neutrophilic lineage, and some CD34+ hematopoietic progenitor cells. FOLR2 is also upregulated on macrophages and monocytes at chronic inflammatory sites including rheumatoid arthritis synovium and glioblastoma.
• Recombinant protein corresponding to aa22-230 from FOLR2, fused to His-Tag at C-terminal, expressed in HEK293 cells.
• Molecular Weight:~25.1kD
• Biological Activity:Measured by its binding ability in a functional ELISA with Folic Acid-BSA. The ED50 range ≤5ug/ml.
• Amino Acid Sequence:QDRTDLLNVC MDAKHHKTKP GPEDKLHDQC SPWKKNACCT ASTSQELHKD TSRLYNFNWD HCGKMEPACK RHFIQDTCLY ECSPNLGPWI QQVNQSWRKE RFLDVPLCKE DCQRWWEDCH TSHTCKSNWH RGWDWTSGVN KCPAGALCRT FESYFPTPAA LCEGLWSHSY KVSNYSRGSG RCIQMWFDSA QGNPNEEVAR FYAAAMHVN＜H HHHHH＞
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.